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– Trough levels should be obtained within 30 minutes before the next scheduled dose. – Weekly vancomycin levels should be obtained for long-term vancomycin use
Adult Dosing Recommendations: Loading dose: • Use a loading dose in: o Serious infections where rapid attainment of target trough level of 15-20 mg/L is
Dosing frequency. Timing of initial vancomycin trough levels ; 6 hourly. Before the 5th dose ; 8 hourly. Before the 4th dose ; 12 hourly. Before the 3rd dose ; 18
AMT Vancomycin and Gentamicin Guidelines. v2011.0) Obtain a serum gentamicin level (trough) before the third dose and twice weekly thereafter (more.Monitor PRE-DOSE (trough) levels at 36 to 48 hours (see Table 2). 5. Adjust maintenance dose according to the current dosing regime and guidance in Table 3.
guidelines on clinical efficacy and tox- of vancomycin dosing and monitoring available in the literature. (SCr) level of ≥0.5 mg/dL, or a 50% in-.
Repeat TDM trough (pre-dose) level every 3 days until levels are stable within the therapeutic range, and at least once weekly thereafter [5, 6]. Unless stated
Vancomycin levels are NOT needed in patients with stable renal function who are on standard doses of vancomycin AND are on therapy for less than 5 days.

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